Skin Substitutes

Advanced Skin Substitutes for Modern Wound Care

Explore a powerful portfolio of regenerative grafts and wound coverings designed to accelerate healing and restore skin integrity.

🌿 Featured Products

At PSP360+, we connect clinics with high-performance skin substitutes and grafts that go beyond standard dressings. From amniotic membranes to collagen-based scaffolds, our curated lineup supports conservative therapy and advanced wound healing protocols.

Whether you're dealing with diabetic ulcers, burns, or surgical wounds, these products are engineered to optimize healing outcomes with minimal complications.

🌿 Amniotic-Based Products

🧬 Collagen & ECM-Based Wraps

💧Hydrated/

Hydrogel Variants

🛡️ Hybrid or Multi-layered Options

🌿 Amniotic-Based Skin Substitute

✅ XWRAP – Amniotic Membrane-Derived Allograft

🧬 Type:

Amniotic Membrane Allograft

✨ What Is It?

A natural amniotic membrane graft used to promote advanced wound healing and tissue regeneration.

🩹 What It’s Used For?

~ Chronic wounds

~ Burns
~ Ulcers
~ Surgical sites needing rapid recovery.

💡 Why Clinics Love It:

~ Minimizes inflammation
~ Accelerates closure

~ Supports regenerative healing.

📦 How It Works:

Delivers a protective biological barrier rich in growth factors to stimulate tissue repair.

📊 Clinical Backing:

Backed by research showing improved healing outcomes compared to standard dressings.

✅ BioLab Sciences – Membrane Graft or Wrap

🧬 Type:

Amniotic Membrane Wrap

✨ What Is It?

A biologically active wrap to cover and protect wounds.

🩹 What It’s Used For?

~ Wound coverage for chronic ulcers
~ Burns or surgical incisions.

💡 Why Clinics Love It:

~ Easy to handle

~ Reduces infection risk
~ Supports faster healing.

📦 How It Works:

Forms a moist healing environment while delivering essential growth factors.

📊 Clinical Backing:

Studies show reduced healing time in chronic wound patients.

✅ Evolution Biologx – SimpliMax

🧬 Type:

Amniotic Membrane Wrap

✨ What Is It?

A premium amniotic graft offering durability, flexibility, and fast integration into the wound bed.

🩹 What It’s Used For?

~ Acute and chronic wounds
~ Surgical sites

~ Trauma care.

💡 Why Clinics Love It:

Long wear time with fewer dressing changes.

📦 How It Works:

Mimics the properties of natural skin to protect and heal.

📊 Clinical Backing:

Proven in clinical trials to accelerate tissue regeneration.

✅ RevoGen Biologics – Revoshield+ Amnio

🧬 Type:

Amniotic Membrane Allograft

✨ What Is It?

A regenerative amniotic allograft designed for fast tissue repair.

🩹 What It’s Used For?

~ Chronic wounds
~ Burns
~ Surgical site healing.

💡 Why Clinics Love It:

Combines protection and regeneration for high-risk wounds.

📦 How It Works:

Delivers bioactive components that reduce inflammation and stimulate repair.

📊 Clinical Backing:

Studies indicate faster healing times and reduced infection risk.

✅ Evolution Biologx – Esano ACA

🧬 Type:

Amniotic Composite Allograft

✨ What Is It?

A composite amniotic graft designed for challenging wounds.

🩹 What It’s Used For?

~ Complex wounds
~ Diabetic ulcers
~ Post-surgical recovery.

💡 Why Clinics Love It:

Strong healing support for patients with slower recovery rates.

📦 How It Works:

Combines amniotic tissue with extra structural support for durability.

📊 Clinical Backing:

Evidence shows improved closure rates for chronic wounds.

✅ DermaBind – Dermabind FM

🧬 Type:

Amniotic Membrane Graft

✨ What Is It?

A flexible amniotic graft that conforms to irregular wound shapes.

🩹 What It’s Used For?

~ Irregular or high-movement wound sites
~ Burns

~ Surgical repairs.

💡 Why Clinics Love It:

Adapts to challenging wound contours while maintaining healing properties.

📦 How It Works:

Forms a secure, moist barrier to accelerate repair.

📊 Clinical Backing:

Demonstrates strong adherence and reduced healing times.

✅ AmchoPlast – Amchoplast

🧬 Type:

Dehydrated Amniotic Membrane Allograft

✨ What Is It?

AmchoPlast is a sterile amniotic graft engineered for advanced wound care. It delivers natural healing factors and a protective barrier in a durable, easy-to-handle format ideal for outpatient and surgical applications.

🩹 What It’s Used For?

~ Diabetic ulcers
~ Surgical wounds
~ Tendon and nerve coverage

💡 Why Clinics Love It:

~ Excellent tensile strength
~ Fast rehydration
~ Flexible and trim-friendly for complex sites

📦 How It Works:

AmchoPlast activates upon hydration, delivering regenerative proteins and reducing inflammation at the wound site while protecting tissue from external stress.

📊 Clinical Backing:

Used across multispecialty clinics for its ability to promote granulation, reduce scar tissue, and integrate seamlessly with native tissue.

🧬 Collagen & ECM-Based Wraps

✅ EnColl – Helicoll

🧬 Type:

Collagen-Based Matrix

✨ What Is It?

A collagen-rich wound matrix that encourages rapid healing.

🩹 What It’s Used For?

~ Chronic ulcers
~ Surgical wounds
~ Burns.

💡 Why Clinics Love It:

Boosts natural collagen production for stronger tissue.

📦 How It Works:

Provides a scaffold for new tissue growth while maintaining moisture.

📊 Clinical Backing:

Evidence supports enhanced healing and tissue strength.

💧 Hydrated/Hydrogel Variants

✅ BioLab Sciences – Membrane Wrap Hydro

🧬 Type:

Hydrated Amniotic Membrane Wrap

✨ What Is It?

A hydro-treated amniotic membrane for moist wound therapy.

🩹 What It’s Used For?

~ Burns, ulcers
~ Post-surgical wounds where hydration aids healing.

💡 Why Clinics Love It:

Keeps the wound moist and promotes natural cell regeneration.

📦 How It Works:

Hydration technology enhances absorption and growth factor delivery.

📊 Clinical Backing:

Clinical evidence supports faster tissue regeneration in moist environments.

🛡️ Hybrid or Multi-Layered Options

Amniotic-Based or Hybrid Substitute (pending manufacturer specs)

Amniotic + Collagen Hybrid (likely composite)

✅ BioLab Sciences – Membrane Tri Layer

🧬 Type:

Triple-Layer Amniotic Membrane

✨ What Is It?

A triple-layer graft for enhanced wound protection and durability.

🩹 What It’s Used For?

Deep or complex wounds needing stronger coverage.

💡 Why Clinics Love It:

Extra strength without sacrificing flexibility or healing power.

📦 How It Works:

Layers create a longer-lasting biological barrier.

📊 Clinical Backing:

Data supports extended wound coverage and fewer dressing changes.

🔬 Conservative Therapy First:
The Power of Collagen Prep

🧠 Collegen Is The Prerequisite For Skin Subs Wound Care

Before grafts, before advanced wound care…
collagen gets the skin ready to heal.

For many patients, the healing journey starts with something simple — daily collagen therapy.

Applied directly to the wound, this powdered or gel-based treatment helps stimulate natural repair and prepares the site for more advanced care like skin substitutes or grafts.

At CSquared360, we don’t just drop products on your desk — we help you build effective wound care protocols.

Conservative therapy is often the key to qualifying patients for biologic treatment and ensuring the best clinical outcomes.

💡 Ready to Get Patients Qualified for Skin Subs?

We handle DME coverage, patient education, and billing compliance —

so you can focus on care while we handle the red tape.
📋 Learn how collagen therapy fits into the process and how we can help you move patients toward advanced biologics with confidence.

🚀 Why CSquared360 ?

Because your clinic deserves more than just billing support.

It deserves a revenue revival — with smarter labs, cleaner billing, and patients who actually find you online.

We’re not just a support system — we’re your growth engine.
Let’s take your practice from slow and scattered to streamlined and scaling.

Let's kick things off with your free billing assessment 💸

That’s right — we’ll identify the leaks in your revenue (and trust us, every practice has some). From there, we connect you with labs that actually get results and plug you into our Local Google Map Pack strategy so your name shows up where it counts.

Because here’s the truth:

If patients can’t find you, they can’t choose you.

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🧠 The Big 3 That Actually Move the Needle:

🧪 Lab Coordination (Built on 20+ Years of Trial, Error & Trust)
Most clinics don’t make money from labs — they just offer it for patient convenience.

But here’s where we’re different:
We’ve spent over two decades testing what works, building relationships, and filtering out the fluff. Now you get access to a trusted network of specialty labs with consistent 72-hour turnarounds, even for advanced panels.

"It’s not about profit — it’s about speed, reliability, and patient trust.
And that means better outcomes, lower stress, and referrals that keep coming back."

📉 Medical Billing
Clean claims. Daily submissions. No contracts.
We don’t just "do billing" — we optimize your revenue cycle and make sure every

dollar gets collected fast.

📍 Google Ranking (Map Pack Domination)
When patients search “clinic near me,” your name should be at the top.
We make that happen — with real optimization that gets the phone ringing.

UNLOCK LOST REVENUE - CLAIM YOUR FREE ASSESSMENTeven if you are under contract, we have solutions to help you switch

Fully Compliant. Unmatched Loyalty.

100% HIPAA-Compliant, 100% Client Retention

Every step of our process is built on full HIPAA compliance and rock-solid operational integrity. But what really sets CSquared360 apart? We’ve never had a single client leave us — ever.

When practices partner with us, they stay.

That’s The CSquared360 Promise.